منابع مشابه
Liposome-Based Flow Injection Immunoassay System
The development of many biochemical assays is dependent upon the specific interaction of an antigen with its antibody. This interaction is usually monitored using secondary labels with the most popular immunoassays employing fluorescent or radioactive tracers for detection of a single binding event. We are developing a novel flow injection analysis (FIA) system which contains an immunospecific ...
متن کاملLiposome-based flow-injection immunoassay for determining theophylline in serum.
We developed a method for quantitatively determining theophylline in serum, using a heterogeneous immunoassay called flow-injection immunoanalysis. The reaction involves competition between serum theophylline and theophylline-labeled liposomes. Separation occurs on a solid-phase reactor column containing immobilized antibody to theophylline incorporated in a flow-injection system. Subsequent ly...
متن کاملIrinophore C: a liposome formulation of irinotecan with substantially improved therapeutic efficacy against a panel of human xenograft tumors.
PURPOSE To assess the pharmacokinetics, tumor drug accumulation, and therapeutic activity of Irinophore C, a novel liposomal formulation of irinotecan (CPT-11). EXPERIMENTAL DESIGN The plasma lactone/carboxy levels of CPT-11 and SN-38 were determined in mice after a single i.v. dose of irinotecan (Camptosar), or Irinophore C, and the plasma t(1/2), plasma area under the curve, plasma C(max), ...
متن کاملTreatment of cytomegalovirus retinitis with intravitreal injection of liposome encapsulated ganciclovir in a patient with AIDS.
To study its safety and efficacy in treating cytomegalovirus (CMV) retinitis, an AIDS patient received an intravitreal injection of liposome encapsulated ganciclovir in the right eye. The left eye served as a control, receiving intravitreal free ganciclovir. The right eye showed no retinal haemorrhages or detachment; however, vision declined initially, stabilising later. Weekly examination show...
متن کاملP 398 Title: Experimental retinal toxicity of intravitreal injection of liposome encapsulated 5-fluorouridine
Eurppse : To evaluate the presence of Neuron Specific Enolase (NSE) in subretinal fluid (SRF? as a uotential marker for retinal damaee and to correlate these b&Vets ‘tith r&al detachment (RD) pzmmwem kS.E is a reliablemarkerofneuronallysisintbecerebro-~fluidinbraindamage. Levels of NSE in the aqueous humour are also elevated in retiwblastoma NSEhaskdetectedinalllayenofnmmal humanretinaexcepth4u...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Hospital Pharmacy
سال: 2017
ISSN: 0018-5787,1945-1253
DOI: 10.1310/hpj5202-144